Pharmacotherapy Utilisation in Alcohol Dependence

8 June 2016

Researchers:

Thompson, A. & Pirmohamed, M.


Wolfson Centre for Personalised Medicine, Institute of Translational Medicine, University of Liverpool, 1-5 Brownlow Street, Liverpool L69 3GL, United Kingdom

Key findings

  • Drug utilisation for severe alcohol dependence is low.
  • Of 43,087 patients, only 11.7% received pharmacotherapy to promote abstinence or reduce consumption in the first 12 months following diagnosis.
  • 1% of patients did not receive psychosocial support or pharmacotherapy in the first 12 months following diagnosis.
  • Males and those from the most deprived areas are least likely to receive pharmacotherapy.
  • Persistence of prescribing appears poor for acamprosate and disulfiram, with less than 31% in both medication groups still receiving the medication after 6 months. This reduces to less than 17% after 12 months.